Ankylosing spondylitis is a chronic inflammatory disorder that primarily involves the sacroiliac joints and the axial skeleton. There is also a variable involvement of peripheral joints and articular structures. Musculoskeletal pain, stiffness, and immobility of the spine due to this is a major burden.
The vertebrae may grow or fuse, resulting in a rigid spine. These changes may be mild or severe and may lead to a stooped posture. Early diagnosis and treatment help in controlling pain and stiffness and may prevent significant deformity.

